Nature Made Extra Strength Probiotics are daily probiotic supplements that work in both small and large intestines to help support digestive balance and healthy gut flora. These gluten free Nature Made Probiotics for adults are dietary supplements that have no color added, no artificial flavors, no preservatives, no dairy, and are 100% vegetarian. Each serving of these probiotics for men and women provides 13 billion CFUs of Lactobacillus rhamnosus GG, which work in the small intestine to help relieve occasional gas, bloating, abdominal discomfort and diarrhea, and 2 billion CFUs of Bifidobacterium lactis HN019, which work in the large intestine to help relieve occasional constipation and irregularity. No refrigeration required(1) with these probiotics for women and men. Adults, take one of these digestive probiotic capsules daily. Nature Made womens and mens probiotics are quality you can trust. (1)Formulated to provide at least 13 billion live cells per capsule of Lactobacillus rhamnosus GG and 2 billion live cells per capsule of Bifidobacterium lactis HN019 if continuously stored in a cool, dry place at or below 77°F (25°C) and consumed prior to expiration date. *Based on a survey of pharmacists who recommend branded vitamins and supplements. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.